How to use Tezspire▼ (tezepelumab)

This is a non-promotional website produced and funded by AstraZeneca, intended for UK patients who have been prescribed TEZSPIRE▼ (tezepelumab)

Coming soon: We are currently updating this website with all relevant information for Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). Please bear with us! You can access Tezspire CRSwNP resources here.

For UK patients, and their caregivers, aged 12 and over who have been prescribed Tezspire (tezepelumab) for severe uncontrolled asthma

For UK patients, and their caregivers, aged 18 and over who have been prescribed Tezspire (tezepelumab) for severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)

For more information read the patient information leaflet accessible here

For UK patients, and their caregivers, aged 12 and over who have been prescribed Tezspire (tezepelumab) for severe uncontrolled asthma

For UK patients, and their caregivers, aged 18 and over who have been prescribed Tezspire (tezepelumab) for severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)

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How to use Tezspire

Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor, pharmacist or nurse if there is anything you are not sure of.

For people aged 12 years and older the recommended dose for Tezspire is 210 mg (1 injection) every 28 days. It is given as an injection under the skin (subcutaneously).

Your doctor or nurse will decide if you can inject yourself or if your caregiver can do that for you. If so, you or your caregiver will receive training on the right way to prepare and inject Tezspire.

Self-injection of Tezspire

It's normal to feel nervous about giving yourself an injection. Once you learn how to take your new medication, you may find it’s much easier than you think. Keep in mind that you’ll only have to do it once every 28 days!

You can either inject with the pre-filled syringe or with the pre-filled pen (do not share these or use them more than once). You can watch a video guide on how to use them, or download the step-by-step guidance.

Full information and 'instructions for use' are also provided in your Tezspire carton, you should read this carefully each time you are injecting Tezspire as there may be new information.

Tezspire pre-filled pen

Click here to download written step-by-step guidance

Tezspire pre-filled syringe

Click here to download written step-by-step guidance

If you have forgotten to inject a dose, inject a dose as soon as possible. Then have your next injection on your next scheduled injection day.
If you did not notice that you missed a dose until it is time for your next dose, simply inject the next dose as scheduled. Do not inject a double dose to make up for a forgotten dose.
If you are not sure when to inject Tezspire, ask your doctor, pharmacist or nurse.

Do not stop using Tezspire without speaking first to your doctor, pharmacist or nurse. Interrupting or stopping the treatment with Tezspire may cause your asthma symptoms and attacks to come back.

Keep this medicine out of the sight and reach of children.
Do not use after the expiry date which is stated on the label and carton. The expiry date refers to the last day of that month.
Store in a refrigerator (2°C to 8°C) in the original package.
Tezspire may be kept at room temperature (20°C to 25°C) in the outer carton for a maximum of 30 days. Once Tezspire has reached room temperature, do not put it back in the refrigerator. Tezspire that has been stored at room temperature for more than 30 days should be safely disposed of.
Do not shake, freeze or expose to heat.
Do not use this medicine if it has been dropped or damaged, or if the security seal on the carton has been broken.

Do not throw away any medicines via wastewater. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Information about the
safety and possible
side effects of Tezspire

Discover resources to
support you on your
treatment journey

Reporting side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk https://yellowcard.mhra.gov.uk. By reporting side effects, you can help provide more information on the safety of this medicine.

▼ This medicine is subject to additional monitoring. This will allow quick identification of new safety information. You can help by reporting any side effects you may get as advised above.

GB-49707 | DOP: March 2024

This is a non-promotional website produced and funded by AstraZeneca.

This site is intended to complement, not replace, the 'Instructions for Use' and 'Patient Information Leaflet' (found in your carton or linked at the top of the page). Refer to these materials for additional important information.

If you have any questions or concerns about your treatment, you should always talk to your healthcare team.

Please see the information in the box above for details on how to report any side effects you may be experiencing.

What to do if you forget to use Tezspire at the usual time

What to do if you stop using Tezspire

How to store Tezspire