Welcome to an AstraZeneca UK produced and funded website
Please select the option that applies to you below.
GB-51556 | DOP: March 2024
For UK patients, and their caregivers, aged 12 and over who have been prescribed Tezspire (tezepelumab) for severe uncontrolled asthma
For more information read the patient information leaflet accessible here
For UK patients, and their caregivers, aged 12 and over who have been prescribed Tezspire▼ (tezepelumab) for severe uncontrolled asthma
For more information read the patient information leaflet accessible here
It is important to know that Tezspire is not a rescue medicine so you should not use it to treat a sudden asthma attack.
If your asthma is not getting any better, or gets worse during treatment with this medicine, speak to a doctor or nurse.
This medicine has been prescribed for you only. Do not pass it on to others as it may harm them, even if their illness seems like yours.
Like all medicines, Tezspire can cause side effects, although not everybody gets them. Scroll down for more information about possible side effects or refer to the patient information leaflet linked at the top of the page. You can also find out how to report side effects at the bottom of the page.
Common side effects (these may affect up to 1 in 10 people)
- Sore throat
- Rash
- Joint pain
- Injection site reaction (such as redness, swelling and pain)
Please talk to your doctor, nurse or pharmacist about what you should look out for when using Tezspire. If you experience any side effects, listed here or not, you should let them know right away.
Serious side effects and important safety information
- Do not use Tezspire if you are allergic to any of its ingredients (tezepelumab, acetic acid, L-proline, polysorbate 80, sodium hydroxide, and water for injections). It's best to check this with your doctor, pharmacist or nurse by discussing with them any known allergies you may have before you start your treatment.
- Patients with a history of allergic reactions, may need to be watched by a nurse or other healthcare professional for a while after receiving a Tezspire injection.
- Talk to your doctor about how to recognise early signs of allergic reactions and what you should do if you spot them.
- Look out for signs of allergic reaction as medicines like Tezspire can potentially cause serious allergic reactions in some people. The signs of these reactions may vary, but can include swelling of your face, tongue, or mouth, breathing problems, fast heartbeat, fainting, dizziness, feeling lightheaded, hives and rash.
If you notice signs of an allergic reaction, speak to a doctor or nurse immediately.
- Look out for any signs of a possible serious infection while you are taking Tezspire, such as:
- fever, flu-like symptoms, night sweats
- cough which will not go away;
- warm, red and painful skin, or a painful skin rash with blisters.
If you notice signs of an infection, speak to a doctor or nurse immediately.
- If you already have a serious infection, talk to your doctor before taking Tezspire.
- If you have a parasitic infection or if you live in (or travel to) an area where parasitic infections are common, talk to your doctor.
Tezspire may weaken your body’s ability to fight certain types of parasitic infections.
- Look out for any symptoms of a heart problem, such as:
- chest pain;
- shortness of breath;
- a general feeling of discomfort, illness, or lack of well-being;
- feeling lightheaded or faint.
If you notice signs of heart problems, speak to a doctor or nurse immediately.
- Do not suddenly stop taking your other asthma medicines when you start Tezspire. This is especially important if you take steroids (also called corticosteroids). These medicines must be stopped gradually, under the supervision of your doctor and based on your response to Tezspire.
- Tell your doctor or pharmacist:
- if you are taking, have recently taken or might use any other medicines.
- if you have recently had or are due to have a vaccination.
- Do not give this medicine to children under 12 years of age because the safety and benefits of this medicine are not known in children in this age group.
- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
- Do not use Tezspire during pregnancy unless your doctor advises it. It is not known if Tezspire can harm your unborn baby.
- Tezspire may pass into breast milk. If you are breast-feeding or plan to breast-feed, talk to your doctor.
- Tezspire is unlikely to affect your ability to drive and use machines.
- This medicine contains less than 1 mmol sodium (23 mg) per 210 mg dose, or per injection, it is basically ‘sodium-free’.
Reporting side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.ukhttps://yellowcard.mhra.gov.uk. By reporting side effects, you can help provide more information on the safety of this medicine.
▼ This medicine is subject to additional monitoring. This will allow quick identification of new safety information. You can help by reporting any side effects you may get as advised above.
GB-49708 | DOP: February 2024
This site is intended to complement, not replace, the 'Instructions for Use' and 'Patient Information Leaflet' (found in your carton or linked at the top of the page). Refer to these materials for additional important information.
If you have any questions or concerns about your treatment, you should always talk to your healthcare team.
Please see the information in the box above for details on how to report any side effects you may be experiencing.
